Welcome to Peptide Cyclization Module for Disulfide Bridge (S-S)

This page is designed so that user can add the di-sulfide bridge between two cysteine residues. A user needs to enter the position of cysteine residues to connect them using disulfide bond. There should be minimum 3 residues between the two cysteine residues involved in disulfide bond formation so as to avoid artifactual structures. For more information click help

Peptide Sequence Submission Form

Peptide sequence in plain text format              

Cysteine positions for di-sulfide bridge (S-S Bond):

Email Address:

Advanced Options:  

Simulation Time: Peptide Environment:
Download topology files: Cluster Analysis:
Download whole trajectory: Energy and RMS graphs:


If you are using PEPstrMOD, please cite the following articles:
i) Singh, S., Singh, H., Tuknait, A., Chaudhary, K., Singh, B., Kumaran, S. and Raghava, G.P.S. (2015) PEPstrMOD: structure prediction of peptides containing natural, non-natural and modified residues. Biology Direct 10:73.
ii) Kaur, H., Garg, A. and Raghava, G.P.S. (2007) PEPstr: A de novo method for tertiary structure prediction of small bioactive peptides. Protein Pept Lett. 14:626-30.
Click Here for PEPstrMOD Manual