CBTOPE- Conformational B-cell Epitope Prediction

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CBTOPE-Algorithm

CBTOPE algorthm is as shown in the diagram.



Figure 1 - Feature extraction for a 19 window length pattern.
Antibody interacting residues are marked in red e.g. S/T, Positive pattern shaded in green where S is at the center with 9 neighboring residues on either side, other overlapping negative patterns are shown in blue.
a) Creation of 19 window overlapping patterns from amino acid sequence, b) generation of binary profile of pattern (BPP), c) generation of physico-chemical profile (PPP) and d) generation of composition profile of pattern (CPP).

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