MHC Class I Binding Peptide Prediction Server

ProPred-I
The Promiscuous MHC Class-I Binding Peptide Prediction Server

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INTRODUCTION

The ProPred-I is an on-line service for identifying the MHC Class-I binding regions in antigens. It implements matrices for 47 MHC Class-I alleles, proteasomal and immunoproteasomal models. The main aim of this server is to help users in identifying the promiscuous regions. Please cite "Singh, H. and Raghava, G. P. S. (2003) ProPred1: Prediction of promiscuous MHC class-I binding sites. Bioinformatics (In Press)" if you use this server in your research. A similar server for MHC Class-II molecules (ProPred: Singh and Raghava, 2001) is available here. For a detailed description, please refer to help page.

SEQUENCE SUBMISSION FORM
Sequence [EXAMPLE]	Paste your sequence
Sequence [EXAMPLE]	Or Submit Sequence
Format	Input sequence format
Allele selection	For multiple selection use the Alt or Meta key
Result	Output Display mode, select one
Threshold	% Of highest scoring peptides
Tabular results	Display top	Peptides
PROTEASOME AND IMMUNOPROTEASOME FILTERS
The peptides with a predicted proteasomal cleavage site will be filtered
Proteasome Filter	Threshold:
ImmunoProteasome	Threshold:

ALL
HLA-A1
HLA-A2
HLA-A*0201
HLA-A*0205
HLA-A*1101
HLA-A24
HLA-A3
HLA-A*3101
HLA-A*3302
HLA-A68.1
HLA-A20 Cattle
HLA-A2.1
HLA-B14
HLA-B*2702
HLA-B*2705
HLA-B*3501
HLA-B*3701
HLA-B*3801
HLA-B*3901
HLA-B*3902
HLA-B40
HLA-B*4403
HLA-B*5101
HLA-B*5102
HLA-B*5103
HLA-B*5201
HLA-B*5301
HLA-B*5401
HLA-B*51
HLA-B*5801
HLA-B60
HLA-B61
HLA-B62
HLA-B7
HLA-B*0702
HLA-B8
HLA-Cw*0301
HLA-Cw*0401
HLA-Cw*0602
HLA-Cw*0702
H2-Db
H2-Db revised
H2-Dd
H2-Kb
H2-Kd
H2-Kk
H2-Ld